top of page

Algorithms

Model specification, simulation and visualization for BioNetGen.

 

Modeling

Uncertain model structure, parallel tempering for parameter optimization, parameter ensemble analysis, Bayesian model selection.

 

Systems

Receptor aggregation (EGFR), endocytosis (EGFR), receptor-mediated signaling (ErbB family, FcεRI receptor, T-cell receptor, EGFR-MAPK-Akt), autophagy (MTORC), transcriptional regulation (Foxp3).

 

Programming

Perl, MatLab, Python, R, BioNetGen (bionetgen.org), rule-based modeling (github.com/RuleWorld/), object-oriented programming.

 

Courses 

Graduate Statistics, machine learning, genomics, molecular evolution, computational structural biology, cell & systems modeling (focus on chemical kinetics).

Undergraduate Protein structure and function, cell biology and signaling, biophysical and biochemical experimental methods.

bottom of page